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益气升白汤治疗乳腺癌化疗后白细胞减少症的临床研究

卡培他滨与卡培他滨联合沙利度胺治疗晚期原发性肝细胞癌的临床研究

脾肾双补汤治疗抗结核治疗中的白细胞减少症的疗效观察

乌苯美司联合化疗对晚期肺癌患者临床疗效和免疫功能的影响

益气生髓汤防治非小细胞肺癌放化疗后白细胞减少症临床研究

Hypoxanthine guanine phosphoribosyltransferase activity is related to 6-thioguanine nucleotide conce

Survival in neutropenic patients with severe sepsis or septic shock

Generic Vancomycin Enriches Resistant Subpopulations of Staphylococcus aureus after Exposure in a Ne

DIAGNOSTIC VALUE OF LEUKOPENIA IN YOUNG FEBRILE INFANTS

Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemother

Risk and Healthcare Costs of Chemotherapy-Induced Neutropenic Complications in Women with Metastatic

Diagnostic value of neopterin during neutropenic fever and determination of disease activity in chil

Comparison of the Kidney Fungal Burden in Experimental Disseminated Candidiasis by Species of the Ca

Outcome of Febrile Neutropenic Patients on Granulocyte Colony Stimulating Factor in a Tertiary Care

Influence of Fungicidal Activity against Candida tropicalis on the Efficacy of Micafungin and Liposo

Incidence of Non-Neutropenic Infection (NNI) in Patients with Follicular Lymphoma and Small Lymphocy

Fulminant Necrotizing Fasciitis Caused by Aeromonas sobria in Neutropenic Patients

Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer pat

Systematic review and meta-analysis of the value of initial biomarkers in predicting adverse outcome

Leucopenia e trombocitopenia induzidas por etanercepte: relato de dois casos e revisão da literatura

应用抗甲状腺药物致粒细胞缺乏患者感染的临床研究
作 者:任蕾,秦贵军,郑丽丽,张会娟,孙良阁,段宇

中华医院感染学杂志 2014年第24卷第17期

【摘要】目的 分析使用抗甲状腺药物(ATD)引起粒细胞缺乏及引发感染患者的临床特点和感染部位、病原菌分布及其耐药性。 方法 回顾性分析72例使用ATD引起粒细胞缺乏及引发感染患者的临床资料,采用SPSS11.0 软件进行统计分析。 结果 72例患者感染部位以呼吸道为主,占55.3%,其次为泌尿系、胃肠道,分别占21.1% 和10.5%;共分离出病原菌52株,其中革兰阳性菌20株占38.5%;革兰阴性菌26株占50.0%;真菌6株占 11.5%;革兰阳性菌对万古霉素和替考拉宁敏感性最高,分别为90.0%和100.0%,对其他抗菌药物均存在不同 程度的耐药性;革兰阴性菌对美罗培南和亚胺培南敏感性最高,均为92.3%,对第三代头孢类药物、阿米卡星等 存在不同程度的耐药性。结论!使用 ATD容易引起患者粒细胞缺乏,继而诱发各种感染,且感染部位以呼吸道 最为常见,引起感染的病菌中革兰阴性菌与革兰阳性菌相当,真菌感染相对较少。

【关键词】抗甲状腺药物;粒细胞缺乏;感染